Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp11 | Arthritis and other joint diseases: translational and clinical | ECTS2014

Multinucleated giant cells in synovia from people with rheumatoid arthritis or osteoarthritis

Prieto-Potin Ivan , Largo Raquel , Roman-Blas Jorge A , Herrero-Beaumont Gabriel , Walsh David A

Aims: To describe different multinucleated giant cell phenotypes and their associations with synovitis in people with rheumatoid arthritis (RA) or osteoarthritis (OA), and in an experimental model of chronic arthritis.Material and methods: A cross-sectional comparative study was performed on samples of knee synovia from age-matched patients with RA, OA, or non-arthritic post mortem (PM) controls. OA synovia were stratified by histological inflammation gr...